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US surgeons successfully test pig kidney transplant in human patient

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For the first time, a pig kidney has been transplanted into a human without triggering immediate rejection by the recipient's immune system, a potentially major advance that could eventually help alleviate a dire shortage of human organs for transplant.

The procedure done at NYU Langone Health in New York City involved use of a pig whose genes had been altered so that its tissues no longer contained a molecule known to trigger almost immediate rejection.

The recipient was a brain-dead patient with signs of kidney dysfunction whose family consented to the experiment before she was due to be taken off of life support, researchers told Reuters.

For three days, the new kidney was attached to her blood vessels and maintained outside her body, giving researchers access to it.

Test results of the transplanted kidney's function "looked pretty normal," said transplant surgeon Dr. Robert Montgomery, who led the study.

The kidney made "the amount of urine that you would expect" from a transplanted human kidney, he said, and there was no evidence of the vigorous, early rejection seen when unmodified pig kidneys are transplanted into non-human primates.

The recipient's abnormal creatinine level - an indicator of poor kidney function - returned to normal after the transplant, Montgomery said.

In the United States, nearly 107,000 people are presently waiting for organ transplants, including more than 90,000 awaiting a kidney, according to the United Network for Organ Sharing. Wait times for a kidney average three-to-five years.

Researchers have been working for decades on the possibility of using animal organs for transplants, but have been stymied over how to prevent immediate rejection by the human body.

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UNICEF ensures 6.1 million people have access to basic health services in Afghanistan

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More than six million people accessed essential health and nutrition services at UNICEF-supported health facilities last month, the UN agency said in its latest Humanitarian Situation Report for September 1 to 30.

UNICEF said of the 6.1 million people who accessed essential health and nutrition services, half of them were children under the age of five.

In addition, 50 schools in 10 provinces gained access to safe water, handwashing facilities, and newly constructed or rehabilitated toilet facilities.

However, as of September, UNICEF’s Humanitarian Action for Children (HAC) appeal for children in Afghanistan is only 41 percent funded.

Afghanistan remains one of the world’s largest humanitarian crises, with 23.7 million people in need of humanitarian assistance following decades of conflict, extreme climate shocks, and severe economic decline.

UNICEF also stated that this year, 33 percent of the population receives most of their income from unsustainable income sources, compared to 26 percent in 2023.

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Polio vaccination campaign kicks off in Afghanistan

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Public Health Ministry officials have confirmed that a polio vaccine campaign across 16 provinces was launched on Monday.

Sharaft Zaman Amarkhil, the spokesperson of the Ministry of Public Health, says that the campaign got underway on Monday in a number of provinces including Kabul, Kandahar, Helmand, Uruzgan, Zabul, Farah, Nangarhar, Laghman, Kunar, Nuristan and some other provinces.

Amarkhil said the campaign will last for three days and an estimated 6.2 million children under the age of five will receive the anti-polio vaccine.

Zaman called on parents, religious scholars and ethnic elders to cooperate with the ministry's vaccinators in implementing the anti-polio vaccination campaign for children under five years old in the mentioned provinces.

The World Health Organization meanwhile published its latest Polio Bulletin on Monday and confirmed Afghanistan has recorded 23 cases of Wild Polio Virus so far this year.

Pakistan meanwhile reported two new cases this week - one in Khyber Pakhtunkhwa province and the other in Balochistan province.

Pakistan has recorded a total of 41 cases of polio so far this year, bringing the total between the two countries to 64, against last year’s total of 12 (Afghanistan 6 and Pakistan 6).
World Polio Day

Marking World Polio Day last week, UNICEF pointed out that the current data issues a stark warning that the life-threatening disease continues to thrive in areas where conflict, natural disasters, humanitarian crises, and other destabilizing factors make it difficult to deliver critical healthcare.

“In conflict, children face more than bombs and bullets; they are at risk of deadly diseases that should no longer exist,” said UNICEF Executive Director Catherine Russell.

“In many countries, we are witnessing the collapse of healthcare systems, destruction of water and sanitation infrastructure, and the displacement of families, triggering a resurgence of diseases like polio. Children are being left paralyzed, unable to walk, play, or attend school."

A global decline in childhood immunization has also led to an increase in polio outbreaks, including in countries that had been polio-free for decades.

Nowhere is this more evident than in conflict-affected areas, with 15 out of 21 such countries – including Afghanistan, Democratic Republic of Congo, Somalia, South Sudan, and Yemen – currently battling polio.

In recent months, UNICEF and partners have intensified emergency responses to surges in polio outbreaks.

In Gaza, for example, UNICEF, in partnership with WHO, reached nearly 600,000 children under 10 years during the first round of a polio vaccination campaign in mid-September. The second and final round has been successfully implemented in south and central Gaza, but renewed mass displacement and bombings have delayed the process in the north.

The campaign follows the return of polio to Gaza for the first time in 25 years.

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AIJU seals deal with private hospital for Afghan media workers

The MoU was signed during a ceremony in Kabul on Tuesday, between Hojatullah Mujadadi, the head of the union, and the director of the private hospital Abdullah Yousafzai.

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The Afghanistan Independent Journalists Union (AIJU) says it has signed a three-year memorandum of understanding (MoU) with a private hospital in Kabul to provide discounted health services to journalists.

The MoU was signed during a ceremony in Kabul on Tuesday, between Hojatullah Mujadadi, the head of the union, and the director of the private hospital Abdullah Yousafzai.

Mujadadi welcomed the move and said this was part of the union’s efforts to ensure media workers are provided with adequate health services.

According to the AIJU, media workers and their immediate families, which include their parents, siblings, spouse and children, will be entitled to substantial discounts for medical treatment at the hospital.

The AIJU said charges would be discounted by between 50% and 70% for media workers.

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