Health
New injection could ‘revolutionize’ treatment of high blood pressure
Drug trials are currently underway in the UK in what some experts have said is a huge breakthrough in treating high blood pressure. Just one injection every six months could lower high blood pressure, trial results suggest.
The new drug, zilebesiran, developed by US-based company Alnylam, is given as an injection rather than in traditional pill form.
High blood pressure, or hypertension, rarely has noticeable symptoms. But if untreated, it increases your risk of serious problems such as heart attacks and strokes.
Persistent high blood pressure can increase your risk of a number of serious and potentially life-threatening conditions, such as:
heart disease
heart attacks
strokes
heart failure
peripheral arterial disease
aortic aneurysms
kidney disease
vascular dementia
The Daily Mail reported that for the drug trials, 107 patients with hypertension were recruited to take part – 80 received a single injection of zilebesiran under the skin, while 32 received a placebo containing no active ingredients.
Five patients who initially received the placebo were later moved to zilebesiran.
Analysis revealed patients who received zilebesiran experienced a substantial reduction in systolic blood pressure – the force with which the heart pushes blood out and round the body – which lasted up to six months.
On average, systolic blood pressure lowered by over 10mmHg at a 200mg dose or more of the drug, and more than 20mmHg at the highest dose of 800mg.
A drop of this size can take someone with high blood pressure to within a much safer range.
Blood pressure naturally goes up and down throughout the course of the day, making it difficult to treat.
But the study found that the drop in blood pressure seen in patients who were treated with zilebesiran was consistent over 24 hours.
Health
Herat Regional Hospital struggling to deal with heavy patient load
Herat Regional Hospital has a capacity to treat about 1,000 patients a day, 650 as in-patients. However, the hospital is being stretched to its limits and is treating more than double this number of people every day, hospital officials say.
Officials say that in most wards, there are two patients per bed. They say the hospital needs to expand - that they urgently need more space and more equipment.
According to doctors, the High Care Unit has only 10 beds, when it actually needs at least 65. In addition, they say the dialysis department is only running at half-mast. It has 17 dialysis machines, but only eight are in working order.
Herat residents have also raised concern over the state of the hospital and said some departments, especially the dialysis unit and pediatrics urgently need equipment and additional space.
Afghanistan is grappling with significant health challenges marked by a fragile healthcare system and unequal access to services, particularly in rural areas.
This is due to a number of issues such as transportation difficulties, shortage of healthcare professionals, and limited access to quality healthcare services.
Despite efforts to improve the country’s healthcare infrastructure, Afghanistan continues to grapple with systemic issues that hinder effective healthcare delivery. Analysis by UN agencies of under-served areas shows that 13.2 million people in 34 provinces reside in areas where primary healthcare services are not accessible within a one-hour walking distance.
Health
Excluding Afghan women from medical institutes threatens the future of health care in the country: MSF
The Islamic Emirate of Afghanistan’s (IEA) decision to bar women from studying in medical institutes will have far-reaching consequences for women’s health in the country, Médecins Sans Frontières (Doctors Without Borders) said on Friday.
This is another stage in the removal of women from public and professional life in Afghanistan. Already, there is an insufficient number of female health care workers in the country, impacting the availability of health care, especially given the separation of hospital wards by gender. New constraints will further restrict access to quality health care and pose serious dangers to its availability in the future, MSF said in a statement.
“There is no health care system without educated female health practitioners,” said Mickael Le Paih, MSF’s country representative in Afghanistan. “At MSF, more than 50 percent of our medical staff are women. The decision to bar women from studying at medical institutes will further exclude them from both education and the impartial provision of health care.”
The medical needs in Afghanistan are huge, and more female Afghan medical staff need to be trained to address them. For this to happen, women need to have access to education. Education restrictions for women and girls put in place in 2024, 2022, and 2021 considerably reduce the number of female medical staff in the future, MSF said.
“If no girls can attend secondary school, and no women can attend university or medical institutes, where will the female health professionals of the future come from and who will attend to Afghan women when they are at their most vulnerable?” said Le Paih. “For essential services to be available to all genders, they must be delivered by all genders.”
Recently, there have been reports that the leader of the Islamic Emirate has ordered the closure of medical institutes to women. The Islamic Emirate has not yet officially commented on this matter.
Health
Afghanistan’s health minister visits disease control center during China visit
Jalali, in China for the World Conference on Traditional Medicine 2024, said that traditional medicine in Afghanistan needs to be regulated and integrated into modern healthcare practices
Afghanistan’s Acting Minister of Public Health has held in depth discussions on managing diseases such as malaria, tuberculosis, and polio with China’s Deputy Director for Disease Control and Prevention, Shen Hongbing.
On an official visit to China, Mawlawi Noor Jalal Jalali also discussed other issues, with Shen and other officials, such as monitoring of diseases, disaster management processes and capacity building for Afghan healthcare workers.
Jalali, who was in China for the World Conference on Traditional Medicine 2024, also toured China’s Disease Control and Prevention Center (CDC) and its National Influenza Center.
The conference, which was held on Tuesday and Wednesday in Beijing, was jointly held by the World Health Organization (WHO) and Chinese sponsors, including China’s National Health Commission.
The opening ceremony of the two-day event was attended by health officials of governments and international organizations, experts and scholars, and deputies from medical institutions.
WHO Director-General Tedros Adhanom Ghebreyesus gave a speech via video.
Addressing delegates at the conference, the ministry cited Jalali as having said that traditional medicine in Afghanistan needs to be regulated and integrated into modern healthcare practices.
He also advocated for strengthened bilateral cooperation between China and Afghanistan to enhance capacity building, experience sharing, and joint research in the sector.
Afghanistan’s health ministry has meanwhile established a Traditional Medicine Department which is currently tasked with formulating policies and guidelines to regulate and improve this sector.
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